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KIP1Kinase Interacting Protein 1
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demonstrated that expression of cell cycle inhibitor p27 KIP1 (encoded by CDKN1B) and p16 INK4a (encoded by CDKN2A) was downregulated in tumor cells.
We found that KIP1 was down-regulated within 1 hr of [E.
It is not clear whether KIP1 is a direct or indirect target of the activated ERs.