L-FABP


Also found in: Medical.
AcronymDefinition
L-FABPLiver-Type Fatty Acid Binding Protein (biochemistry)
L-FABPLiver Cytosolic Fatty Acid Binding Protein
L-FABPLevels of Fatty Acid Binding Protein
References in periodicals archive ?
Recent studies also showed that renal markers such as cystatin C, NGAL, L-FABP, KIM-1 and IL-18 are proposed as potential biomarkers for CI-AKI.
Similarly, Dede et al.13 concluded that RIRS was a safe procedure after finding no significant differences in the urine KIM-1, NGAL, NAG, and L-FABP levels before and after RIRS.
Urinary L-FABP levels were significantly increased in macroalbuminuric patients compared with microalbuminuric and currently normoalbuminuric patients [46].
The tumor cells lack immunoexpression of L-FABP because it is down-regulated in HA-H.
L-FABP is a small cytoplasmic protein that binds long-chain fatty acids, and may have a role in fatty acid uptake, transport and metabolism.
KIM-1, IL-18, and L-FABP are other well-studied biomarkers that have the same limitations as NGAL.
In the brain and intestine, brain-type fatty acid protein (B-FABP) and intestine-type fatty acid protein (I- FABP) are tissue-specific, but H-FABP and L-FABP are co- expressed.1
TOFA, C75) may also be bounded by L-FABP and targeted to induce PPAR[alpha] transcription of fatty acid [beta]-oxidative enzymes in mitochondria (CPT1A, rate limiting; CPT2) and peroxisomes (ACOX1, rate limiting).
L-FABP and I-FABP expression in newborn rats changes inversely in the model of necrotizing enterocolitis.
Over a series of exemplary reports, researchers from the laboratories of Schroeder and Spener have provided convincing evidence that L-FABP directly interacts with PPAR[alpha] and is involved in the nucleo-cytoplasmic shuttling of activator ligands [36, 39, 41, 46, 47, 49, 50].