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LCADLaguna College of Art and Design (Laguna Beach, CA)
LCADLong-Chain Acyl-CoA Dehydrogenase (inherited metabolic disease)
LCADLiverpool Centre for Arts Development (Liverpool, England, UK)
LCADLightweight Chemical Agent Detector (military technology; UK)
LCADLincoln Council on Alcoholism and Drugs, Inc. (Lincoln, Nebraska)
LCADLinn County Ambulance District (Brookfield, MO)
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Abbreviations FFAs: Free fatty acids MS: Metabolic syndrome ROS: Reactive oxygen species PPARs: Peroxisomes proliferative activator protein UCPs: Uncoupling proteins IMS: Intermembrane space MIM: Mitochondrial inner membrane MOM: Mitochondrial outer membrane RXR: Retinoid X receptor Cyt c: Cytochrome c PUFAs: Polyunsaturated fatty acids LCFA: Long chain fatty acid LCAD: Long chain PC: Palmitoyl carnitine.
The manner in which the LCAD performs is dependent on the grid structure, more specifically on the ch-node's position inside it.
Besides, the mRNA levels of medium- and long-chain acyl-CoA dehydrogenase (MCAD and LCAD) and carnitine palmitoyl transferase-1[beta] and -2 (CPT-1[beta] and CPT-2) were notably decreased by isoproterenol, which could be partially reversed by Rapa (P < 0.01 versus model); however, the effect of Rapa on upregulating these genes associated with fatty acid metabolism was abrogated by the pretreatment of TNF-[alpha] (20 ng/mL) (Figures 5(f) and 5(g)).
SUPPORT: Pauline Ashley (LCAD), Peter Rix (Vision), Bill Staples (CENTEC), Richard Stowe (NEET), Colette Casey (LCDA), Tom Stowe (NEET) and Kenneth Cheung (BEEcycle)
Other energy-dissipating tissues expressing PPARs do not seem to contribute to this phenotype as oxidative target genes in skeletal muscle [long chain acyl-CoA dehydrogenase (LCAD) and pyruvate dehydrogenase kinase 4 (PDK4)] and in brown adipose tissue [uncoupling protein 1 (UCP1) and PPAR[gamma] coactivator 1[alpha] (PGC-1[alpha])] were not affected (Figure 4B,D).
Pictured are LCAD Faculty Member Robin Fuld, LCAD President Dennis Power, First Thursday's Art Walk President Charlie Ferrazzi and LCAD Associate Director of Development Tracy Otto.
TABLE 1 Disorders Included in the Screening Program in June, 2004 Disease Analyte MCAD C6, C8, C10:1 VLCAD C14:1, C16:1, C14 LCAD C16, C18:1 SCAD C4, C4/C2, C4/C3 CPT II C16, C18:1 GA II C4, C5, C6, C5/C3 PA C3, C3/C2 GA I C5-DC MMA C3, C3/C2 IVA C5, C5/C3 3 MMC C5-OH b-KT C5:1, C5OH HMGCoA Lyase deficiency C5-OH, C6DC TABLE 2 Diseases included in the National Neonatal Screening Program in Costa Rica * Disease Analyte Method Break point Congenital Hypothyroidism TSH IFMA 16_Ul/ml Phenylketonuria Phenylalanine BIA 4mg/dl Maple Syrup Disease Leucine BIA 4mg/d1 Congenital Adrenal Hyperplasia (+) 17 - OHP IFMA 20ng/ml Galactosemia (+) Galactose EFA 12.8mg/dl * See Table 1 for the most recently included diseases (+) Pilot Study 1999-2000.
They found that the enzyme called LCAD was "hyperacetylated" and contained even more acetyl groups than usual and the enzyme had reduced activity.
The decision to run the course in Capital of Culture year was the brainchild of Ms Stapleton and LCAD director Val Bayliff.
The evening included a compelling speech by LCAD student Nicholas Enevoldsen, silent auction, raffle and a live auction.