LCDD

AcronymDefinition
LCDDLight Chain Deposition Disease
LCDDLinear Collider Detector Description (software)
LCDDLes Chevaliers Du Destin (French: Knights of Destiny; online gaming)
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References in periodicals archive ?
LCDD is a multisystem disease usually associated with plasma cell dyscrasias or multiple myeloma.
Renal involvement is seen very commonly in LCDD, presenting as proteinuria, nephrotic syndrome or renal insufficiency.
(2,5,6) Four other reported cases of isolated liver LCDD and patients with both liver and renal involvement showed either mild liver enlargement and/only mild to moderate abnormalities in LFT.
Three subtypes of MIDD are recognized depending on the composition of immunoglobulin deposits: LCDD, in which the deposits are composed of monoclonal light chains only; light and heavy chain deposition disease (LHCDD), in which the deposits are composed of monoclonal light and heavy chains; and heavy chain deposition disease (HCDD), in which the deposits are composed of monoclonal heavy chains only [3].
We believe this case report represents the first report of LCDD from Saudi Arabia.
Clinically, most patients with LCDD (as illustrated in this report) present with nephrotic range proteinuria and rapidly deteriorating renal function [9].
Among the PCD patient groups, the FLC results were comparable to published retrospective data for patients with NSMM, AL, LCDD, and MGUS.
In addition, the FLC and IFE data validate our retrospective studies that indicated that the FLC assays are more sensitive than individual serum or urine IFE assays for detection of FLCs in AL and LCDD (1).
Lastly, the FLC assay is useful for monitoring disease activity in patients with NSMM, LCMM, AL, and LCDD in whom there is no measurable M-spike on serum or urine protein electrophoresis.
These 47 frozen sera had been collected from AL, LCDD, or MM patients: 24 samples were from patients with a monoclonal [kappa] light chain and 23 from patients with a monoclonal [lambda] light chain.
Sera from 19 patients with LCDD were obtained from the Dysproteinemia Clinic frozen serum bank.
The results for 19 LCDD patients are listed in Table 5.