Midfielders: Edwin Tenorio (Barcelona, SC), Edison Mendez (LDU
), Patricio Urrutia (LDU
), Cristian Lara (El Nacional), Segundo Castillo (El Nacional), Luis Antonio Valencia (Recreativo Huelva, Spain), Luis Fernando Saritama (Deportivo Quito).
It's 34 games unbeaten for La U now and despite LDU
Quito's pedigree in South America's top competitions, it's difficult to see them upsetting the favourites, so the 7-1 makes no appeal.
Quito have a great recent record in South America's cup competitions, with success in this tournament in 2009 as well as glory in the more prestigious Copa Libertadores in 2008.
Best prices - 90 minutes: 1-2 Velez Sarsfield (general), 13-2 LDU
Quito (Victor Chandler), 3 draw (Victor Chandler).
Paraguay's Enrique Vera plays his club football for Ecuadorian giants LDU
Libertad scored an impressive 2-0 victory at home against Sao Paulo to advance in the previous round of the competition, but face a tough task subduing a LDU
Quito side that has won six of its last seven matches, and are seeking to regain the Copa Sudamericana crown they won in 2009.
Recommendation Quito-Draw double chance 1pt 11-10 Hills, Stan James MATCH BETTING BET365 BFRED BLUE SQ BOYLE CORAL HILLS LADS POWER S JMS VC Independiente 8-11 4-5 8-11 8-11 4-6 7-10 4-5 5-6 8-11 3-4 LDU
Quito 4 3 10-3 10-3 10-3 19-5 3 11-4 15-4 15-4 Draw 5-2 9-4 9-4 9-4 12-5 12-5 9-4 12-5 5-2 12-5 Best-price percentage: 103 HANDICAP start received (+) by Estudiantes BET365 BFRED BLUE SQ HILLS POWER S JMS VC Handicap +17.5 +17.5 +17.5 +16.5 +16.5 +17.5 +17.5 Regal Barcelona 10-11 17-20 10-11 17-20 5-6 10-11 10-11 Estudiantes 10-11 17-20 10-11 17-20 5-6 10-11 10-11
Home specialists LDU
Quito may be the best of the outsiders as altitude played a key part in their 2008 success, while Velez are Argentina's best hope.
Pachuca are competing in the tournament for the third time and they will be looking to improve on their 2008 effort, when they advanced to the semi-finals before losing 2-0 to South American champions LDU
PLAYERS OUT: Ander Herrera (PSG, free), Antonia Valencia (LDU
Quito, free), James Wilson (Aberdeen, free), Regan Poole (MK Dons, free), Matty Willock (Gillingham, free), Matthew Olosunde (Rotherham, free), Kieran O'Hara (Burton, loan) KEY MAN: Marcus Rashford CHANCES: With the honeymoon period now over for former caretaker boss Ole Gunnar Solskjaer, securing a return to Champions League football is the absolute minimum target.