LITAFLPS (Lipopolysaccharide)-Induced TNF (Tumor Necrosis Factor) Alpha Factor
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To investigate the function of LILRB1 and LILRB3 genes for growth factor activation, 3 chemokine (CCL-4, CXCL-13, and CXCL-14) and 12 cytokine (IL-1[beta], IL-4, IL-6, IL-10, IL-12p40, IL-17A, IL-17F, IFN-[alpha], IFN-[beta], IFN-[gamma], LITAF, and TGF[beta]4) genes in the immune cell were measured by qRT-PCR.
Molecular cloning and characterization of chicken lipopolysaccharide-induced TNF-alpha factor (LITAF).
For this purpose EGR2, MPZ, PMP22, CX32, HSP22, HSP27, LITAF, LMNA, MFN2, NEFL and HSN2 were screened and we did not found any mutation.
Litaf: Lemida yexidanit, tipulit, pe-ila (Litaf (Acronym): Individualized, remedial, active learning).
TABLE 1 Clinical and genetic classification of hereditary motor and sensory neuropathy, with the linked locus and gene if known (Pestronk 2004) Pattern of Inhe- CMT-Type ritance Phenotype Locus Gene (s) Demyeli- Dominant CMT1A 17p11 PMP22 nating CMT1B; CMT1E 1q22 MPZ CMT1C 16p13 LITAF CMT1D 10q21 ERG2 CMT1F 8p21 NEFL HNPP l7p11 PMP22-deletion HMSN3 (Dejerine- PMP22/MPZ/ Sottas) EGR2/8q23 Thermosensitive ?
Analysis of chicken TLR4, CD28, MIF, MD-2, and LITAF genes in a Salmonella enteritidis resource population.
Amar, "LPS-induced TNF-[alpha] factor (LITAF)-deficient mice express reduced LPS-induced cytokine: evidence for LITAF-dependent LPS signaling pathways," Proceedings of the National Academy of Sciences of the United States of America, vol.
Quantitative real time polymerase chain reaction (qRT-PCR) oligonucleotide primers for chicken lipopolysaccharide-induced tumor necrosis factor-a factor (LITAF), tumor necrosis factor superfamily 15 (TNFSF15), interleukin-8 (IL-8), and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) internal control are listed in Table 2.
The levels of mRNAs encoding IL-10, lipopolysaccharide-induced TNF-[alpha] factor (LITAF), and TNF superfamily member 15 (TNFSF15) in intestinal epithelial and spleen cells were not affected by either treatment (data not shown).