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Lupus miliaris disseminatus faciei (LMDF), also termed acne agminata or acnitis, is a rare granulomatous skin disease mainly affecting the central area of the face.7 It shows a characteristic tendency to involve the lower eyelids.1-3 Lesions may occur singly or in crops.6 In the early lesions, there is perivascular and periappendageal lymphomononuclear cell infiltration.
LMDF was also considered to be a variant of lupus vulgaris because of the histology, but there has been no evidence to date supporting a link to tuberculosis.1,2 Evidence against this association includes a variable cutaneous hypersensitivity response to tuberculin, the absence of bacilli in lesions, failure to respond to antituberculous therapy in many cases and failure to demonstrate the DNA of M.
LMDF has frequently been regarded as a variant of granulomatous rosacea (GR).1,2,6 The predominance in young adults, involvement of extrafacial sites and areas typically spared by rosacea (lower eyelids), and the absence of erythema, flushing and telangiectasia argue against LMDF being a form of rosacea.1,10,11 Furthermore, LMDF has variable response to oral tetracyclines, an occasional response to oral steroids and a self- limited course with scarring, inconsistent with the diagnosis of rosacea.1,10 Although dermal
The don described the LMDF's project as admirable and worthy of praise and further support from government and wealthy individuals in the society,' she said.
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