LREA - What does LREA stand for? The Free Dictionary
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According to the statistical results summarized in Table 1, the hypothesis that the residual variance equaled a constant as the independent variable (SG) increased could not be rejected for the LREA case.
It may be deduced from Figures 2 and 3 that the predicted embedment gap for any given SG is higher for the LRAA orientation compared to the LREA orientation.
In particular, laboratories that use Sanger sequencing are strongly encouraged to use a mutated allele-enriching strategy, such as locked nucleic acid or peptide nucleic acid clamps, coamplification at lower denaturation temperature PCR, or enzymatic digestion of wild-type sequences, to enhance the sensitivity for the common critical mutations in exon 19 (747_750 LREA
deletions), 20 (T790M), and 21 (L858R).