The LSRO was unable to find reliable published evidence that proved or disproved the hypothesis that mercury from dental amalgams harms pregnant women or their infants.
LSRO and FDA admit that amalgams release mercury vapor.
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To achieve its goal, however, GOED needed to understand the current thinking on these nutrients from the regulators' perspective, which is why LSRO
brought the regulators and scientists together.
LSRO says while post-market surveillance programs are similar across a variety of product categories since they follow similar information processing principles, in the dietary supplements sector, voluntary post-market surveillance is uncommon and no accepted surveillance standards exist.
LSRO was asked to determine how a system for handling consumer inquiries could be tailored to the task of monitoring the safety of dietary supplements.
The LSRO in conjunction with an expert committee of scientists completed its study in two phases.
Analyses of MET IDRs and a review of existing surveillance programs led the LSRO experts to make several recommendations, which they noted should be broadly applicable to dietary supplements and not to any one particular type of supplement or manufacturer.