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Prolonged APD results in longer open state of LTCCs and NCX and longer [Ca.sup.2+] transient.
During rest, depolarization of the CM membrane by inward current of sodium activates LTCCs leading to CICR and contraction.
CACNA1C encodes the [alpha]1C subunit of the LTCC ([Ca.sub.v]1.2 subtype), which is the main subunit of LTCC and is also the target of many antidepressant drugs.
Caption: Figure 4: Whole-cell patch clamp analysis of CHO cells with LTCC constitutive expression.
During the time I was PVA national president, we pushed the VA to build more SCI centers and to begin construction of long-term care centers (LTCC).
Nevertheless, direct evidence for the effects of CBG on L-type [Ca.sup.2+] channels (LTCC) is lacking.
Application of Ver (0.1 mM), a specific LTCC blocker, nearly completely blocked [I.sub.Ca-L] (Figure 2(a)) (P < 0.01), indicating that these currents were [Ca.sup.2+] currents.
WE6A-5: A Miniaturized LTCC Multi-layered Front-end Module for Dual Band WLAN (802.11a/b/g) Applications
Packaging techniques discussed in the session include highly integrated LTCC applications, LTCC implementation techniques, and a low-cost plastic packaging approach.
Calcium regulatory proteins are mainly composed of L-type Ca[sup]2+ channels (LTCCs), ryanodine receptor 2 (RyR2), and Na[sup]+/Ca[sup]2+ exchanger (NCX).
Expression of LTCC, RyRs, and IP[sub]3 Rs subtypes in the same tissue might occur in various combinations.,, We measured mRNA and protein expression of Cav1.2, Cav1.3, IP[sub]3R1, IP[sub]3R2, IP[sub]3R3, and RyR2 in lower esophageal smooth muscles [Figure 1]a and [Figure 1]e.
In response to this expressed need, NIST is working together to support the materials design and measurement needs of the emerging LTCC industry.
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