As shown in [Table 2], the thickness of IVS and
LVPW;d significantly increased in SBHF patients compared with those of CONS (IVS: 12.14 [+ or -] 1.17 vs.
Cardiac hypertrophy was commonly assessed by ventricular mass and ventricular wall thickness, indicated by HW/BW, LVW/BW, LVAW, and
LVPW [20].
However the LVPWd and
LVPWs and IVSd and IVSs were significantly increased (Fig.
The most common echocardiographic finding was septal hypertrophy, seen in 16 (50%) cases, followed by LV posterior wall hypertrophy (
LVPW) in 14 (43.8%) and LV dilatation in 8 (25%) cases.
The LV wall thickness values, including IVS and
LVPW, were significantly increased in mice subjected to TAC in diastolic phase.
If compared to the non-obese subjects, the obese had significantly higher values of the LV relative wall thickness (0.44 [+ or -] 0.06 vs 0.39 [+ or -] 0.03, p <0.0001 for the IVS and 0.42 [+ or -] 0.06 vs 0.38 [+ or -] 0.04, p <0.0001 for the
LVPW).
Indicative parameters include LV mass and heart-to-body weight (or femur length) ratio,
LVPW and septum thicknesses, LV internal diameters, and cardiomyocyte size.
Left ventricular end-diastolic dimension (LVEDD), left ventricular end-systolic dimension (LVESD) interventricular septum (IVS) and LV posterior wall thickness (
LVPW) dimensions in diastole, aorta and pulmonary artery dimensions, right ventricular dimension were measured by standard M-mode guided by two-dimensional echocardiogra-phy.
As proposed by the ASE [13], linear internal measurements of the left ventricle and its walls are performed in the parasternal long-axis view with a two-dimensional (2D) echocardiography-guided M-mode approach, including left atrial systolic diameter (LAD), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), interventricular septal thickness (IVST), and left ventricular posterior wall thickness (
LVPW).
Echocardiogram revealed hypertrophic cardiomyopathy with left ventricular posterior wall (
LVPW) thickness of 9 mm and interventricular septum (IVS) thickness of 9 mm.
M-mode and 2-dimensional echocardiographic images were obtained from parasternal long- and short-axis views for assessment of LV end-diastolic diameter (LVEDD), LV end-systolic diameter (LVESD), LV posterior wall thickness (
LVPW), interventricular septum thickness in diastole (IVS), LV ejection fraction (LVEF), and fractional shortening (LVFS).
Moreover, Dox treatment for 4 days led to decreases in systolic left ventricle posterior wall thickness (
LVPW; s), LV volumes during both systole and diastole, and FS% (Table 1).