LXR


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AcronymDefinition
LXRLinux Cross Reference
LXRLiver X Receptor (molecular biology)
LXRLuxor, Egypt - Luxor (Airport Code)
LXRLogic extension Resources (software developer)
LXRLoyola/Xavier/Ryder (Georgetown University; Washington, DC)
LXRLate Xenograft Rejection
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References in periodicals archive ?
The hotel, which will be known as The Biltmore, Mayfair - LXR Hotels & Resorts, has undergone a multimillion-pound redevelopment following its closure in early July 2018.
RGX-104, an orally-administered potent small molecule agonist of the LXR, was able to deplete MDSCs both in cancer patients participating in the dose escalation portion of the Phase 1a/b trial and in mice.
Recently, evidence shows that some kinds of cancer, such as melanoma, colon, lung, and kidney tumors inhibit the function of DCs through LXR activation by releasing LXR ligands or oxysterols [17].
StAR overexpression stimulates cholesterol efflux by activating LXR and stimulation of ABCA1 expression.
Three, most important families of transcription factors regulating these processes could be distinguished: sterol regulatory element binding protein (SREBP), liver X receptors, (LXR), and carbohydrate response element binding protein (ChREBP) [12-15].
Cholesterol homeostasis is intricately regulated by a battery of transcription factors among which LXRs are nuclear receptors that play a crucial role in transcriptional regulation of lipid metabolism and inflammation (Ostlund, 1993) Activated LXRs form a heterodimer with the retinoid X receptor [alpha] (RXR[alpha]), which binds to LXR responsive elements (LXREs) and consequently promotes target gene expression (Zelcer and Tontonoz 2006).
Russell, "Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice," Cell Metabolism, vol.
This acquisition also adds VTP-38543, a topical LXR? (Liver X Receptor beta) selective agonist for the potential treatment of atopic dermatitis.
Effect of garlic on lipid profile and expression of LXR alpha in intestine and liver of hypercholesterolemic mice.