LYQLutheran Youth of Queensland
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Correspondence should be addressed to Yiqun Liu; and Liang Ding;
In addition to these exon 1 mutations, there are three major polymorphisms in the promoter region of the MBL gene, which are expressed as four haplotypes called HYP, LYP, LXP, and LYQ. The X/Y polymorphism at position -221 is important because the X haplotype is highly prevalent [~24% in Caucasian populations (3)] and is associated with low circulating MBL concentrations, comparable to those of the structural variants B, C, and D (4).