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LTD4Leukotriene D4 (lipid mediator)
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Montelukast inhibits the actions of leukotriene D4 (LTD4) by reversibly binding on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes.
Serhan, "Selectivity of recombinant human leukotriene D4, leukotriene B4, and lipoxin A4 receptors with aspirin-triggered 15-epi-LXA4 and regulation of vascular and inflammatory responses," The American Journal of Pathology, vol.
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Modulation of leukotriene D4 attenuates the development of seizures in mice.
Metabolomic markers Malondialdehyde 4-Hydroxyhexenal 4-Hydroxynonenal Hexanal Heptanal Oktanal Nonanal Decanal Undodecanal 3-Nitrotyrosine 8-Hydroxy-2'-deoxyguanosine 5-Hydroxymethyluracil o-Tyrosine 3-Chlorotyro sine 8-Isoprostane Leukotriene B4 Proteomic markers Leukotriene D4 Interleukin 6 Interleukin 8 Monocyte chemotactic protein-1 Epidermal growth factor Soluble transferrin receptor LG3 fragment of endorepellin Tumstatin Endostatin BOX 2: Urinary markers that differentiated all groups of subjects: group 1 (healthy controls), group 2 (IgAN patients), and group 3 (disease controls).
Nagata, "Eosinophil superoxide anion generation induced by adhesion molecules and leukotriene D4," International Archives of Allergy and Immunology, vol.
Phahmacology of Montelukast sodium (Singulair), a potent a selective leukotriene D4 receptor antag onist.
The cysteinyl leukotriene D4 receptor antagonist montelukast for the treatment of interstitial cystitis.
Effects of 6 weeks of therapy with oral doses of ICI 204,219, a leukotriene D4 receptor antagonist, in subjects with bronchial asthma.
Hu et al., "Leukotriene D4 induces amyloid-[beta] generation via CysLT1R-mediated NF-[kappa]B pathways in primary neurons," Neurochemistry International, vol.
Leukotriene D4 receptor antagonist montelukast alleviates protamine sulphate-induced changes in rat urinary bladder.