One method is IT-based drug discovery, while the other combines conventional low-molecular-weight
drug discovery technologies with computer-based compound screening.
The authors conducted a literature search to identify randomized trials that compared unfractionated heparin with control, low-molecular-weight
heparin with control, low-molecular-weight
heparin with unfractionated heparin, or a selective factor Xa inhibitor (fondaparinux) with placebo for reducing DVT, pulmonary embolism (PE), or mortality in hospitalized medical patients.
Pooled results of the trials that compared the two agents showed that low-molecular-weight
heparin was more effective in preventing deep vein thrombosis, reported Lironne Wein, of the department of epidemiology and preventive medicine at Australia's Monash University, Melbourne, and her associates.
polyolefins as extrusion lubricants for rigid PVC.
heparin was designed to behave more predictably in the body, thereby making monitoring unnecessary.
Location was unaffected by the use of low-molecular-weight
In cancer patients, low-molecular-weight
heparin results in lower risk of recurrence of venous thrombosis and a reduced risk of major bleeding, compared with warfarin," Mohammad Jahanzeb, M.
The continuous phase, which has the tan [Delta] peak temperature at about -50 [degrees] C, consists primarily of natural rubber and a low concentration of low-molecular-weight
ends of the resin.
Furthermore, the Company is in pre-clinical development with a number of product candidates, including a low-molecular-weight
heparin patch for thromboses, a parathyroid hormone analog transdermal patch for osteoporosis, and an atypical antipsychotic transdermal patch for the management of psychoses.
Although aspirin, unfractionated heparin, and low-molecular-weight
heparin are all treatment options, alone or in combination, not enough evidence currently exists to recommend any specific regimen over the others.
Unfractionated heparin and low-molecular-weight
heparin are equally effective for the treatment of acute venous thromboembolism (VTE) in pregnancy (strength of recommendation [SOR]: C; based on expert opinion and 1 low-power cohort study).