LO

(redirected from Lysyl oxidase)
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AcronymDefinition
LOLittle One (child)
LOLeft Out
LOHello
LOLaw and Order
LOLights Out
LOLoan Officer
LOLearning Object
LOLiceum Ogolnoksztalcace (Polish high school)
LOLamar Odom (basketball player)
LOLay Out (design)
LOSlovakia
LOLecco (Italy)
LOLog Out
LOLocal Oscillator
LOLearning Organization
LOLake Oswego (Oregon)
LOLearning Outcome (education)
LOLiaison Officer
LOPolish Airlines (IATA airline code)
LOLandsorganisationen (central organization for the Swedish Worker's Trade Unions)
LOLandsorganisasjonen
LOLake Orion (Michigan city)
LOLutte Ouvrière (French: Workers' Struggle, Reunion)
LOLocals Only (surfing slang)
LOLandsorganisationen I Sverige (Swedish trade union)
LOLease Option
LOLesson Objective (education)
LOLichamelijke Opvoeding
LOLevel Off
LOLubricating Oil
LOLiquid Oxygen
LOLearning Objective
LOLow Observable
LOLodi, Lombardia (Italian province)
LOLandelijke Organisatie (Dutch)
LOLunar Orbit
LOLager Onderwijs
LOLubrication Order
LOLife Orientation
LOLine Office
LOLaser Optics
LOLeave Without Pay
LOLandscape Ontario (Canada)
LOLysyl Oxidase
LOLao Language (language code; International Organization for Standardization)
LOLocked Open
LOLocal Optimization
LOLyra's Oxford (Phillip Pullman book)
LOLeft Oophorectomy (gynecology)
LOLicensed Optician
LOLiner Out (shipping)
LOLetter Orders
LOLine of Operation
LOLight Offense (gaming)
LOLeadership Oakland (Troy, Michigan)
LOLiquid Oxidation
LOLaboratory Outfitting
LOLow Nuc Inbackhaul Check (airfare construction)
LOLandsorganisatie (Dutch)
LOCarriers' Official Stamp (Scott Catalogue prefix; philately)
References in periodicals archive ?
Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation.
The preliminary data strongly suggest that lysyl oxidase inhibition alters the collagen architecture and restores it to the normal architecture found in the skin," Iyer says.
1999), causes stabilization of fibrinogen and up-regulation of copper-dependant enzymes, such as lysyl oxidase, important for matrix remodelling (Kobayashi et al.
Copper is also required for the activity of lysyl oxidase, an enzyme required for the cross-linking of collagen and elastin.
Some of the mechanisms responsible for this reduction are increased elastase activity,6 decreased serum elastase inhibitor level, decreased elastin gene expression, abnormal copper metabolism/copper deficiency and low lysyl oxidase activity.
For example, expression of the hypoxia-regulated gene LOX (lysyl oxidase) predicts relapse in human breast tumors (28), but recent studies suggest that systemic secretion of lysyl oxidase into the lung and liver might facilitate the homing of disseminated cancer cells to these organs through the formation of a prometastatic microenvironment (29).
The enzyme called lysyl oxidase (LOX) has been found to stiffen collagen, a major component of the supportive tissue in the breast.
Copper deficiency decreases the activity of lysyl oxidase and impairs the cross-linking of collagen in bone of experimental animals.
Through a molecular approach called differential display analysis, Hendrix's team identified the gene lysyl oxidase and a zinc finger transcription factor in highly aggressive breast cancer cells that spread.
A collagen-specific enzyme, lysyl oxidase, crosslinks these trimers into fibrils or meshworks.