MATCIMiniature Analytical Thermal Cycling Instrument
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This required considerable redesigning of hardware and software originally developed for MATCI to accommodate the order of magnitude increase in capability.
This variability did not cause problems for the MATCI, in which a single PCR routine controlled one chip.
Our previous reports on the single microchip PCR instrument, the MATCI, utilized conventional sample preparation methods to detect hantavirus in rodent blood (14) and orthopoxvirus in Vero cells (16).