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He further stated that initially, the MCAC would be entrusted with appeals against orders, civil revisions, appeals in rent and family cases.
The inhibitory rates of MCACs on HEp-2 and HL-7702 cells at the concentration of 20 [micro]M were shown in Supplementary Table.
The [beta]-diketonate structure in curcumin is modified in MCACs (Figure 1(a)), which could improve its chemical stability in a different way .
Therefore, we synthesized 34 MCACs and screened out CA15 which performed a stronger inhibitory effect on laryngeal cancer cells HEp-2 but a lower toxicity on hepatic cells HL-7702 compared to curcumin (Table 2).
Caption: FIGURE 1: Design and synthesis of MCACs (a), chemical structure of curcumin analogue CA15 (b), and molecular docking of CA15 with MD2 (PDB ID 2E56).
This is important when attempting to assess the MCACs and their effect on backbench cohesion.
As one MP explained, MCACs "respond to the concern of a lot of MPs who were being blindsided too often and wanted to have input" (MP8).
MCACs stand in contrast to MPs' customary engagement with government policy proposals only at the last minute in full caucus, where time is short and the executive has already decided its position.
While it is recognized that MCACs are advisory and that ministers retain the final decision on what proposals to bring forward, MPs also believe that their views, by virtue of inclusion in the MC, are given consideration at the cabinet phase.
Federal Judicial Academy (FJA) director general Hayat Ali Shah briefed the meeting on the Expeditious Justice Initiative-II (EJI-II) regarding strategy for establishment of the Model Civil Appellate Courts (MCAC) and the Expeditious Justice Initiative-III (EJI-III) regarding strategy for establishment of the Model Trial Magistrate Courts (MTMC).
On Monday Hayat Shah informed the NJPMC that under EJI-II, it was proposed that MCAC might be introduced in all districts of Pakistan for which the respective high courts will nominate presiding officers/additional district judges.
Initially, MCAC will be entrusted with appeals against orders, civil revisions, appeals in rent and family cases whereas the nominated judicial officers would be entrusted with 100 old cases at a time.
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