Change in Size of Detached Cell-Area with mDBD Plasma Treatment Time.
Effect of mDBD Plasma on Viability of Lung Adenocarcinoma Epithelial Cells.
mDBD Plasma-Induced Apoptosis in Lung Adenocarcinoma Epithelial Cells.
Cells were analyzed using flow cytometry and the apoptotic effect of mDBD plasma was assessed after 24 h of plasma treatment.
A549 lung cancer cells were treated with mDBD plasma for various treatment times.
On day 0, immediately after mDBD plasma treatment (and after 1 hour of sample preparation), 40% of detached cells were dead in all experimental groups (Figure 5(a)) suggesting cell death immediately after plasma treatment.
In addition to detachment, the viability of cells decreases due to apoptotic cell death induced by mDBD plasma.
This mDBD plasma has shown promising results in inducing apoptosis in A549 cell line in vitro.