On the same day, we changed antibiotics from MEPM
In those cases with shock, MEPM was used most often (51.6 %) and in cases without shock, tazobactam/piperacillin (TAZ/PIPC) was used most often (21.7%); importantly, there was a significant difference in the use of antimicrobial agents between the cases with shock and without shock (p=0.0324).
We also showed a significant difference in antibiotic usage between the cases with shock and without shock, suggesting that even though it cannot be known if antibiotic usage is the result or cause, MEPM was often used in the cases with shock and TAZ/PIPC in those without; this finding may be evidence for urosepsis cases and shock.
** The United Democratic Forces consists of the Union of Democratic Forces (SDS), the Democratic Party (DP), the Gergyovden Movement, the Bulgarian Agrarian National Union --United (BZNS-united), and the Roma Movement for an Equal Public Model (MEPM
On day 6, the SBT/ABPC and CPFX treatment was changed to meropenem (MEPM; 3 g/day) and levofloxacin (LVFX; 500 mg/day).
BT, body temperature; CPFX, ciprofloxacin; CRP, C-reactive protein; MEPM, meropenem; SBT/ABPC, sulbactam/ampicillin; [SpO.sub.2], percutaneous oxygen saturation.
After the results from blood cultures on day 69 of admission, vancomycin (VCM) (1 g every 6 hours) was added to the therapy, while TAZ/PIPC was changed with meropenem (MEPM
) (1 g every 6 hours) on day 72.