MEWDSMultiple Evanescent White Dot Syndrome
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DISCUSSION: MEWDS is an inflammatory chorioretinopathy that affects mainly young, healthy women in the second to fourth decades of life.
Choroidal scarring resembling multifocal choroiditis may develop in some patients, especially those with chronic MEWDS.
Because MEWDS has a self-limited course, no specific treatment is necessary.
The aim of the present report was to describe an unusual cluster of seven cases of MEWDS encountered within a 3-month period, with an emphasis on the clinical presentation and multimodal imaging findings.
A retrospective observational study was conducted in seven patients who presented with MEWDS between July and September 2013 at two tertiary medical centers in central Israel.
Neurological evaluation including full neurological exam and neuroimaging excluded additional neurological deficit, before the diagnosis of MEWDS was established.
MEWDS. MEWDS, first described by Jampol et al., presents with numerous small, discrete white lesions in the deep retina or level of the RPE and appears in the posterior pole and extends to the midperiphery [29].
In evaluating the current literature for MEWDS, data was obtained from 3 articles (Table 3) [13,31, 32].
MFC, unlike classic APMPPE and MEWDS, is more likely to have irreversible visual damage and impairment (Figure 4).
Patients presenting with MEWDS underwent a comprehensive ocular examination with the best-corrected visual acuity (BCVA), biomicroscopy, color fundus photography, autofluorescence imaging, fluorescein (FA), and indocyanine green angiographies (ICGA).
Four patients presenting with MEWDS were included in this study.
The recent use of C-scan allows, for the first time, a new and comprehensive description of acute lesions in MEWDS and abetter understanding of the physiopathological process of this disease.