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MIAMEMinimum Information About a Microarray Experiment
MIAMEMinimal Information About A Microarray Experiment
MIAMEMember of the Institute of Automotive Mechanical Engineers (Australia)
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Indeed, we already have good guidelines for many aspects of reporting, including both MIAME (2) and REMARK (reporting recommendations for tumor marker prognostic studies) (9).
Other than the generally accepted MIAME convention, there is little standardization for reporting orthogonal data relevant to interpretation of microarray results (e.
To assess the current level of MIAME compliance in miRNA array studies, I reviewed articles that reported array-based miRNA profiling in the 4 journals that published the largest number of such studies during a 10-month period in 2011-2012.
2] Nonstandard abbreviations: IOM, Institute of Medicine; NCI, National Cancer Institute; FDA, US Food and Drug Administration; CALGB, Cancer and Leukemia Group B; CTEP, Cancer Therapy Evaluation Program; IDE, investigational device exemption; IVDMIA, in vitro diagnostic multivariate index assay; IRB, institutional review board; GEO, Gene Expression Omnibus; MIAME, Minimum Information about a Microarray Experiment.
After the very favorable response that the MIAME received from the microarray community and key scientific journals (Ball et al.
2] Nonstandard abbreviations: NRI, Net Reclassification Index; STROBE, Strengthening the Reporting of Observational Studies in Epidemiology; STARD, Standards for Reporting of Diagnostic Accuracy; REMARK, Reporting Recommendations for Tumor Marker Prognostic Studies; MIAME, Minimum Information about a Microarray Experiment; CONSORT, Consolidated Standards of Reporting Trials.
There are numerous significant challenges in generating and sharing validated data obtained from gene expression analysis systems, including sample preparation and storage and the type and extent of data that are necessary to describe any microarray experiment, as outlined by the MIAME (Minimal Information About Microarray Experiments) Conference (7).
Authors should continue to take primary responsibility for ensuring that all data collected and analyzed in their experiments adhere to the MIAME (Minimum Information About a Microarray Experiment; http://www.
Other groups are promoting the use of specific data formats such as the MIAME (Minimum Information About a Microarray Experiment) standards for content, as well as the accompanying MAGE (MicroArray and Gene Expression) data format standards developed by the Microarray Gene Expression Data Society.
To answer this need, the Minimal Information about a Microarray Experiment, or MIAME standard, has been proposed by the MGED (http://www.
MIAME (Minimum Information About a Microarray Experiment)-compliant microarray data are available as supplementary information and submitted to the Gene Expression Omnibus (GEO) database (GEO 2004).