In this study, all EEP showed an antimicrobial effect against Staphylococcus spp isolates, MIC90
= 60 - 30 mg/mL, irrespectively of microbial resistance of the isolates.
of cefovecin against Staphylococcus intermedius was 0.
Values of MIC50 MIC90
MIC range and mode for clinical strains.
Behera et al (22) reported MIC90
values of tigecycline against MRSA and VRE as 0.
The MIC at which 50% and 90% of the isolates were inhibited (MIC50 and MIC90
respectively) was determined for each year (Table 2).
of 1 mg/L against these isolates was the most favorable of the 10 drugs tested.
The MIC at which 90% of the strains tested were inhibited (MIC90
) from these samples was compared with MIC90
values previously reported from travelers to the same regions in 1997 (Antimicrob.
is the minimum inhibitory concentration of the drug that is required to decrease growth of 90% of the pathogen.
In contrast, antibiotics that rely on time-dependent killing, such as [beta]-1actams, macrolides, azalides, tetracyclines, and some others, require extended durations of concentrations above the MIC90
of the bacterial pathogen(s).
The highest MIC90
for Pseudomonas sp were observed with cefotaxime, ceftriaxone, ampicylim, cefoxitin, cefazolin, cefuroxime cephalotin, vancomycin, ampicylim/sulbactam and amoxicillin/ clavulanic acid.
Study conclusions: On a MIC90
(Minimum Inhibitory Concentration required to inhibit the growth of 90% of organisms) basis, dalbavancin was more potent than vancomycin, linezolid or daptomycin for every organism group studied.
of ceftazidime against 50 isolates of Acinetobacter baumannii was >128 mg/L whether avibactam was present or not, which is consistent with this species not being listed on the drug label.