Nitric oxide synthase modulates the antihyperalgesic effect of the NMDA receptor antagonist MK-801
on carrageenan-induced inflammatory pain in rats.
Memantine is a non-competitive NMDA receptor antagonist, with peculiar pharmacological properties, which explain its excellent safety and tolerability profile, at variance with the most potent NMDA receptor blockers such as ketamine, phencyclidine, and MK-801
Each main group was also divided into 3 subgroups in order to subject the animals to MK-801
induced hyperlocomotion, apomorphine-induced climbing, and haloperidol-induced catalepsy tests seperately.
and NMDA was simultaneously added to [Mg.sup.2+]-free Locke's buffer in the NMDA + MK-801
Paliperidone protects prefrontal cortical neurons from damages caused by MK-801
via Aktl/GSK3(3 signaling pathway.
Control group received saline, and MK-801
group received MK-801
Continuous co-administration of dextromethorphan or MK-801
with morphine: Attenuation of morphine dependence and naloxone-reversible attenuation of morphine tolerance.
Gilbert and Burdette, 1996; Applegate et al., 1997; Yoshida et al., 1997; Krug et al., 1998) and there are abundant evidence that MK-801
could also induce neuronal damage in a dose-dependent manner (Peng et al., 2013).
is a noncompetitive antagonist of NMDA receptor.
We demonstrated that central delivery of the NMDA antagonist MK-801
disrupted the acquisition of preferences for a grape flavor paired with a carbohydrate (polycose) in hungry rats.
We have previously shown that radial glia decrease their filopodial process motility in vivo in response to intraventricular application of the N-methyl-D-aspartate receptor (NMDAR) blocker MK-801
gunden itibaren 10 gun sure ile gunde 2 kez olmak uzere enseden derialti (subkutan) MK-801
enjeksiyonu yapilmistir (dizocilpine 0.25 mg/kg dozda ve 0,1 ml/20gr vucut agirligi hacminde).