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The assay leverages its core single nucleotide polymorphism (SNP)-based massively multiplexed PCR (mmPCR) technology to accurately measure dd-cfDNA levels without the need for donor genotyping and it has been clinically validated.
The blinded study, conducted in collaboration with the University of California, San Francisco (UCSF), leveraged Natera's massively-multiplexed PCR (mmPCR) technology to measure dd-cfDNA levels in plasma collected on the same day as a kidney biopsy from 193 unique kidney transplant recipients.
The company said the data demonstrates superior performance of its massively-multiplexed PCR (mmPCR) technology for detecting acute rejection in kidney transplant patients.