MRCNSMethicillin Resistant Coagulase-Negative Staphylococci
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Among 57 CNS 17 (29.8%] were MRCNS, while 40 (70.2%] were MSCNS.
The susceptible phenotype (ERY-S, CLI-S) was detected in 25 (67.6%), five (22.7%), four (28.6%), and seven (23.3%) of MSSA, MRSA, MSCNS and MRCNS, respectively (Table 1).
In this study, the frequency of MSSA (25; 67.6%) was greater than MRSA (five; 22.7%) and of MSCNS (four; 28.6%) was lower than MRCNS (seven; 23.3%).
n=53 (34.4%) MRCNS n=29 (18.8%) viridans group streptococci n=21 (13.6%) methicillin- susceptible coagulase-negative staphylococcus (MSCNS) n=20 (13%) Bacillus spp.
The most commonly detected microorganism was MRCNS (n=43) followed by
Resistant bacteria MRSA plus MRCNS was 68.8%) in patients with a history of hospitalisation while it was 22.2% in those without (p=0.011).
During the second half of 2011, the detection rates of MRSA and MRCNS were 60.13% and 85.54%, respectively.
All the 130 MRCNS isolates were found to be susceptible to vancomycin as they did not show any growth on vancomycin screen agar.
(3) Also, 100% susceptibility of CNS to vancomycin and teicoplanin in the current study could be due to the preferential use of linezolid by clinicians in our hospital; and glycopeptides are not uniformly administered to treat infections caused by MRCNS. The emergence of resistance may be as a result increasing selective pressure of vancomycin due to its widespread use to treat infections caused by staphylococci (methicillin resistant isolates; in particular) and other gram-positive cocci.
Comparing the results of conventional method with molecular method among 110 staphylococci, 18 were tube coagulase, femB and mecA positive (MRSA), 52 were tube coagulase and femB negative and mecA positive (MRCNS).
haemolyticus was the predominant MRCNS isolated followed by S.