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References in periodicals archive ?
But MRD reveals that the two species co-existed for about 100,000 years, the scientists said.
Saylor and her colleagues combined the field observations with analysis of microscopic biological remains to reconstruct the landscape, vegetation and hydrology where MRD died.
MRD refers to the presence of cancer cells that remain detectable, despite a patient having achieved complete remission by conventional assessment.1 The presence of MRD is broadly considered the most important independent prognostic factor in ALL.2-8 MRD is only measurable through the use of highly sensitive testing methods that detect cancer cells in the bone marrow with a sensitivity of at least one cancer cell in 10,000 cells--versus about one in 20 with a conventional microscope-based evaluation.1,9,10
The associations between MRD status and clinical outcomes were analyzed by the Kaplan-Meier method or calculated using cumulative incidence curves to accommodate competing risks.
The research has shown that combining the results of MRD analysis with genetic profiling doctors will be able to significantly improve the accuracy of predicting relapse of the disease and improving treatment options.
Taking into account key genetic abnormalities will ensure that MRD thresholds for more or less intensive chemotherapy are more flexible and each child gets the most appropriate treatment.Dr Anthony Moorman
Quantitative variables like age, vertical interpalpebral fissure height (IPFH) and marginal reflex distance (MRD) were analyzed before and after surgery at 4, 8, 12 and 24 weeks and presented in form of mean +- S.D.
The diagnosis and MRD monitoring of Tunisian ALL are commonly achieved through morphological and cytogenetic methods.
The combination of BDO and MRD is subject to customary closing conditions and is expected to be completed on November 1, 2016.
This valuation includes the assumption of MRD's net debt, which was USD 1.1bn as of 31 March 2016.
The researchers found that MRD testing was far superior at predicting relapse compared to current methods, which mainly rely on analysis of genetic abnormalities within individual patients' cancer cells that influence whether they are "high risk" or "low risk" at the start of treatment.
There was no statistically significant difference found with respect to age, preoperative MRD, preoperative amount of ptosis, and preoperative levator function between the two groups as shown in Table 1.