MROD was increased in 15- (1.5-fold) and 90- (1.3-fold) day-old, but slightly decreased (23%) in 30-day-old MPR rats.
Analysis of ethoxycoumarin-O-deethylation (ECOD), ethoxyresorufin-O-deethylation (EROD), methoxyresorufin-O-demethylation (MROD), pentoxyresorufin-O-depentylation (PROD), benzyloxyresorufin-O-debenzylation (BROD) and p-nitrophenol hydroxylation (PNPH) activities measured in liver microsomes from 15-, 30-, 60- and 90- day-old offspring from dams fed either a 0% protein (MPR groups) or a standard diet (C groups) during the first ten days of lactation.
NAVSEA ISSUED REF A AND B RECOMMENDING THE REMOVAL OF THE REVERSE OSMOSIS DESALINATOR (MROD) FROM 688 AND 774 CLASS SUBMARINES.
REMOVE MROD FROM STOWAGE LOCATION, DOCUMENT THE TRANFER ON 1149 AND SHIP MRODS TO: N60138 DDNV-N CHEATHAM ANNEX WAREHOUSE 1, C STREET POC: JOHN LEONARD WILLIAMSBURG, VA 23185.
(39) reported that TEQ predicted the effects on ethoxyresorufin-O-deethylase (EROD) or methoxyresorufin-O-deethylase (MROD
) activities (strict dioxin-like effects), but not pentoxyresorufin-O-deethylase (PROD) or circulating serum thyroxine levels.
The 1989 MROD changed the tunnel plug to a flow-through design, converted the temporary water-treatment facility to a permanent one, and changed the process from lime softening to high-density sludge treatment (HDS).
High-density sludge (HDS) treatment, specified in the MROD as the treatment technology to be used, is not the only method that could be used in this situation, Conventional water treatment with pH adjustment would be equally effective.
Enzymatic markers of cytochrome P450 1A1 and 1A2 induction, ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-deethylase (MROD), were used as they are AhR-mediated responses and are common to TCDD and dioxin-like PCBs.
On a weight basis, lot 6024 induced significantly greater MROD activity than lot 124-191 (Figure 2A).
During the past few surveys, I noticed personnel are not aware of the Planned Maintenance System (PMS) MIP: 5940/001 (Q-1R) for the Manual Reverse Osmosis Desalinator (MROD
), step 1h., requires the sailor to "Place the unit in a plastic bag." Previous Force Revisions (FR) listed a plastic bag which did not fit the device.