MRP8


Also found in: Medical.
AcronymDefinition
MRP8Migration Inhibitory Factor-Related Protein 8 (cellular biology)
MRP8Myeloid Related Protein 8
References in periodicals archive ?
Strupat, "Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 detected by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry," Journal of the American Society for Mass Spectrometry, vol.
Ludwig et al., "Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock," Nature Medicine, vol.
The HGNC approved names of genes encoding for MRP8 and MRP14 are S100A8 and S100A9, respectively.
Calprotectin exists as a noncovalently complexed hetero dimer of two calcium and zinc binding proteins MRP8 and MRP14.
MRP8 could merely be detected in parental EPG85-257P cells at a very low level.
Myeloid-related protein 8 (MRP8, S100A8) and MRP14 (S100A9) are the most abundant cytoplasmic proteins in neutrophils.
Goebeler et al., "MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes," Blood, vol.
Increased coexpression of CFTR and S100 calcium binding proteins MRP8 and MRP14 mRNAs in cystic fibrosis human tracheal gland cells.
Arakaki et al., "Accumulation of macrophages expressing MRP8 and MRP14 in skin lesions during Leishmania major infection in BALB/c and RAG-2 knockout mice," Parasitology International, vol.
Thus, MRP8 or MRP14 and their heterodimeric complex, MRP8/14, seem to be key proteins in cell-cycle regulation and cell activation with calcium to motivate phagocytosis (14-16).
Voskort et al., "The toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells," Nature Medicine, vol.
Sorg, "MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner," Blood, vol.