MTF1Metal Transcription Factor-1
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Additionally, the FHL3 gene was very close linked to the MTF1 gene on chromosome 6.
A retrospective case-control study with 255 patients evaluated possible associations between single nucleotide polymorphisms (SNPs) in the ATM, XRCC1, TP53, XRCC3, and MTF1 genes with associated PTC risk.
In silico analyses indicate that rs4149182 in OAT3 is situated in a binding site for metal-regulatory transcription factor 1 (MTF1), and that the C > G transversion results in loss of the MTF1-binding site.
The availability and use of transcription inducers, such as metal-regulatory transcription factor-1 (MTF-1), are important for MT expression, and SNPs in MTF1 were also genotyped (Karin a al.