GC has become the most popular first-line chemotherapy regimen in Europe and North America based on Von der Maase trial results, which demonstrated similar survival between patients treated with GC versus MVAC
with better safety profile , although response rates to these regimens are high but not durable with median overall survival of only 12 to 15 months for patients with advanced disease [3,8].
Finn et al., "A prospective randomized trial comparing MVAC
and CISCA chemotherapy for patients with metastatic urothelial tumors," Journal of Clinical Oncology, vol.
(3) Chemotherapy regimens are high-dose intensity MVAC
(methotrexate, vinblastine, doxorubicin, and cisplatin) and PCG (paclitaxel, carboplatin, and gemcitabine).
Giannatempo et al., "Long-term efficacy and safety outcomes of modified (simplified) MVAC
(methotrexate/vinblastine/doxorubicin/cisplatin) as frontline therapy for unresectable or metastatic urothelial cancer," Clinical Genitourinary Cancer, vol.
It was determined that MVAC
was too narrow in its focus and that it was important to look at how training could be provided to other industries and fields in Michigan.
for Advanced Renal Medullary Carcinoma: Report of Three Cases and Literature Review.
Our institution previously reported on 111 patients who received neoadjuvant methotrexate-vinblastine-doxorubicin-cisplatinum (MVAC
) chemotherapy followed by TURBT.
For example, MVAC
protocol comprises of four drugs including methotrexate, vinblastine, cloxorubicin and cis-platin.
The regimens consisting of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC
) and gemcitabine and cisplatin (GC) are currently employed and provide prolongation of survival up to 14.8 and 13.8 months, respectively .
Prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC
. J Clin Oncol.
When vectoring you for an approach or departure, the controller refers to either a Minimum Vectoring Altitude Chart (MVAC
) or an En Route Minimum IFR Altitude (MIA) Chart to determine the lowest altitude that provides the required obstacle clearance (ROC).
is a voluntary consortium of the DAU Midwest Region; Wright-Patterson Air Force Base, Ohio; universities who provide educational programs on base (Central Michigan University and Embry Riddle Aeronautical University); Miami Valley universities such as the University of Dayton, Wright State University, and Central State University; two Miami Valley community colleges (Clark State Community College and Sinclair Community College), and the Miami Valley Tech Prep Consortium.