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In this configuration, resources for the MVAP that were unused during the disconnection period are incorporated into the process of funding the debt for the user's reconnection.
Average number of subscribers and beneficiaries of MVAP in Bogota.
Rate limiting bottlenecks have been proposed at single specific steps in both the MVAP and JH-branch in the CA of different insects, including upstream of the acetyl-CoA pool  as well as by rate limiting blockages at different enzymatic steps in the pathway, including the activities of HMGR [158,159], farnesol dehydrogenase , farnesal dehydrogenase , or JHAMT [7, 77].
Branch point regulation is an important mechanism controlling carbon flow in the MVAP; the FPP produced by the MVAP can be shunted to many metabolic branches for the synthesis of critical molecules such as ubiquinone, dolichol, or prenylated proteins .
In the CA, some MVAP precursor pools might be controlled by feedback regulation imposed by metabolites such as FPP operating in the downstream portions of the pathway, in a similar mode to the negative feedback of late MVAP precursors (GPP, FPP) on the activity of mevalonate kinase described for terpene homeostasis in mammals .
What do integrated studies of CA transcripts, enzyme activities, and metabolites tell us about the coordination of MVAP and JH-branch activities?
The main mechanism in the pathogenesis of MVAP is based on the repeated micro-aspiration of microorganisms that colonize the upper airways through the space between the endotracheal tube cuff and trachea wall.
Due to the importance of MVAP and the consequences for patient survival and healthcare costs, a study to characterize MVAP is performed in the Hermanos Ameijeiras Hospital (HAH) annually.
Clinical diagnosis of MVAP was performed following the Clinical Pulmonary Infection Score (CPIS).
The antimicrobials assessed to compare the resistance of the Acinetobacter baumannii and Pseudomonas aeruginosa strains isolated from patients with and without MVAP were: amikacin (10 [micro]g), ampicillin (10 [micro]g), ampicillin-sulbactam (10 [micro]g-10 [micro]g), aztroenam (30 [micro]g), cefepime (30 [micro]g), cefoxitine (30 [micro]g), ceftazidime (30 [micro]g), ceftriaxone (30 [micro]g), ciprofloxacin (5 [micro]g), colistin (10 [micro]g), gentamicin (10 [micro]g), imipenem (10 [micro]g), meropenem (30 [micro]g), nalidixic acid (30 [micro]g), and tigecycline (15 [micro]g).
From the 61 patients included in this research, 28 (45.9%) and 23 (37.7%) had diffuse and localized infiltrates, respectively, which are relevant signs of MVAP. 35 patients (53.73%) showed an infiltrate score [greater than or equal to] 6 according to CPIS (9) and three (4.90%) were diagnosed post-ventilation.
total minority voting age population ("MVAP"), and Democratic
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