Examples are KLF4 mRNA and miR-206 in quiescent cells and
Myt1 and miR-16 in immature oocytes, which are illustrated in Figure 2 [85,100,103,104].
A critical balance between Cyclin B synthesis and
Myt1 activity controls meiosis entry in Xenopus oocytes.
We also examined activation of other kinases, Wee1 and
Myt1, that phosphorylate Cdc2 at Tyr15 to maintain Cdc2 in an inactive state.
Analysis of the SPP1 promoter sequence revealed putative transcription factor binding sites for SP1 around c.-66, for CBFA1/RUNX2 around c.-155, and for
MYT1 zinc finger factor at c.-443 (Fig.