MZBCLMarginal Zone B Cell Lymphomas
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Although MZBCL and LPL share many overlapping immunophenotypic features, the immunoglobulin heavy chain expressed by monotypic PCs from LPL is nearly always immunoglobulin (Ig) M, in contrast to the typical IgM expressed in MZBCL.
A, This extranodal MZBCL has a focal area of monocytoid differentiation (upper left) and plasmacytic differentiation (lower right corner).
SLL/CLL 80-92 LPL 9-43 MZBCL Splenic MZBCL 20 Nodal MZBCL 8.