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The main reasons why children are more susceptible to methemoglobinemia include inadequate soluble form of the nicotinamide adenine dinucleotide (NADH)-cytochrome b5 reductase enzyme, which deoxidizes MetHb and facilitates oxygen transport, fetal Hb being more sensitive to oxidation, and intestinal colonization with nitrate-producing bacteria.
The blue color in her skin, mucosa, and urine were due only to MetHb. Isosulfan blue stain-induced methemoglobinemia was diagnosed based on knowledge of the use of the stain due to the characteristics of the surgical procedure, the high methemoglobin concentration both in arterial blood gas analysis and in further biochemical blood analysis, and the decrease in Sp[O.sub.2] saturation regardless of normal Pa[O.sub.2].
For patients who do not successfully respond to supportive therapy or who have substantially higher than normal levels of metHb, methylene blue with adjuvant activated charcoal can be considered as a legitimate and intact treatment option.
W toku diagnostycznych badan toksykologicznych potwierdzono methemoglobinemie--stezenie MetHb wynosilo 46,5%.
Pure human methemoglobin (metHb), myoglobin from equine skeletal muscle, and L-cysteine were purchased from Sigma (St.
After 12 hours, we obtained normal oxygen saturation and there was no requirement for inotrope agents; MetHb and lactate levels were decreased gradually.
A homogeneous preparation of bovine Hb was obtained from bovine hemoglobin (MP Biomedicals, Germany), which was a mixture of methemoglobin (metHb) and oxygenated hemoglobin (Hb[O.sub.2]).
Although approximately 1-3% of total Hb remains in oxidized form and it is known as methemoglobin (metHb), cell-free Hb is always in oxidized form due to reaction of Hb with environmental oxygen.
Carboxyhaemoglobin (HbCO) and methaemoglobin (MetHb) are formed after CO and haemoglobin combine (Alp et al 2004).
It could be possible that rbcNOS-derived NO was being scavenged by oxyhemoglobin (Hb[O.sub.2]) under normoxic conditions via conversion to MetHb and nitrate (Wennmalm et al.
There was no significant difference (P greater than 0.05) in the mean values of MetHb of groups A, B and C
Cyanosis is recognized in patients with methemoglobin (MetHb) concentrations higher than 1.5 g/dl (1), (2).