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References in periodicals archive ?
Pulmonary Function and the Methacholine Challenge Test. The methacholine challenge test was performed according to published guidelines [17], with a doubling of the concentration of the methacholine solution (0.25, 0.5, 1, 2, 4, 8, and 16 mg/mL methacholine) in normal saline.
A methacholine challenge test "can be useful, but not entirely diagnostic" because 10% of normal, nonasthmatic individuals react to a challenge, she said.
A methacholine challenge test should be performed in future long-term, follow-up studies, as it was the only test that measured a significant long-term benefit to ribavirin therapy.
If their physician is hesitant to give a diagnosis of asthma without wheezing, a spirometry or methacholine challenge test should be done.
Laviolette replied that in dog studies, a favorable response to the methacholine challenge test is present at 3 years and counting.