MEVA

(redirected from Mevalonic aciduria)
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AcronymDefinition
MEVAMevalonic Aciduria (autosomal recessive metabolic disorder)
MEVAModular Effectiveness Vulnerability Assessment
MEVAMilitary Equipment Valuation and Accountability (business process)
MEVAMission Essential Vulnerable Area
MEVAManitoba Electric Vehicle Association (Winnipeg, Manitoba, Canada)
MEVAMunicipalities Enabling and Validating Act (Victoria, British Columbia, Canada)
MEVAMalaysian Equine Veterinary Association
MEVAMise En Valeur Agricole (French: Agricultural Development; Ministry of Agriculture, Livestock, and Fisheries; Madagascar)
References in periodicals archive ?
The more severe phenotype is mevalonic aciduria (MA), usually associated with MVK enzyme activity less than 0.5%.
The disease is caused by different MVK mutations, which elicit clinical signs ranging from the milder hyperimmunoglobulinemia-D syndrome (HIDS) to its most severe expression, named "mevalonic aciduria." However, autoinflammatory attacks in HIDS can even be complicated by macrophage activation syndrome [25].
A closely related disease is mevalonic aciduria (OMIM 610.377), which is due to a near-total inactivity of the enzyme mevalonate kinase: in this condition, recurrent fever episodes appear in association with serious systemic signs, such as delayed growth, cranial-facial dysmorphism, microcephalia, cerebellar atrophy, ataxia, psychomotor retardation, retinal dystrophy, and cataracts [108].