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References in periodicals archive ?
Microarray experimentation is one of the fastest-growing methods used in genomic research and has led to a broad diversity of microarray databases in both the public domain and commercial domains (Gardiner-Garden and Littlejohn 2001).
Various research organizations maintain a host of smaller "core" databases, including the holdings of the Microarray Center at the NIEHS National Center for Toxicogenomics (NCT) and the Stanford Microarray Database at Stanford University.
Such a microarray database, GEO (Gene Expression Omnibus), is already up and running at the National Center for Bioinformatics (13).
Gene Expression Specifications: Another objective of MIAME was to guide the development of microarray databases and data management software.
Public microarray databases include NCBI, Genbank, Array Express, Gene Expression Omnibus, and Stanford Microarray [14].
The structure of this paper is as follows: In the next section, microarray databases are described in general, along with the details of the proposed methods.
Subsequent chapters examine topics such as the design of microarrays for the analysis of gene expressions; standard clustering approaches for gene microarray data analysis; modeling affymetrix data at the probe level; Bayesian analysis of microarray data; false discovery rate and multiple comparison procedures; using standards to facilitate interoperation of heterogeneous microarray databases and analytic tools; and combining high dimensional biological data to study complex diseases and quantitative traits.