(redirected from Mineralocorticoid Receptor Antagonist)
MRAMagnetic Resonance Angiography
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References in periodicals archive ?
Major studies on mineralocorticoid receptor antagonist therapy (eplerenone) in central serous chorioretinopathy Eplerenone Authors Study design dose 25 mg/g (1 week), Prospective, uncontrolled followed by 50 Bousquet et al.
The council advises that management of resistant hypertension includes maximization of lifestyle interventions, use of long-acting thiazide-like diuretics (chlorthalidone or indapamide), and addition of a mineralocorticoid receptor antagonist (spironolactone or eplerenone).
The proceeds from the series A will be used to expand the business and operational structure of the company, including the opening of global corporate headquarters in the Greater Philadelphia Area, to advance the clinical development of its lead candidate KBP-5074, a mineralocorticoid receptor antagonist for cardiovascular disease entering Phase 2b; and to support other promising programs in the pipeline.
Meanwhile, treatment with mineralocorticoid receptor antagonist should also be considered as another option.
Schneider et al., "Mineralocorticoid receptor antagonist treatment in bilateral chronic central serous chorioretinopathy: a comparative study of exudative and nonexudative fellow eyes," Retina, vol.
receptor antagonist losartan, ACE inhibitor captopril, calcium channels blocker amlodipine, and mineralocorticoid receptor antagonist spironolactone for 21 days (5 mg/kg of body weight, per day), by gavage.
As serum potassium remained low, at approximately 2.8 mmol/L, he was switched from amiloride to eplerenone, a mineralocorticoid receptor antagonist that does not cause gynecomastia.
Medical management includes treatment with a mineralocorticoid receptor antagonist such as spirinolactone.
Spironolactone is a mineralocorticoid receptor antagonist and thus effectively the antifludrocortisone.
Eplerenone, a selective mineralocorticoid receptor antagonist currently approved by the Food and Drag Administration for treatment of hypertension, reduces mortality following myocardial infarction (MI) in patients with left ventricular dysfunction and clinical signs of congestive heart failure.
However, when a mineralocorticoid receptor antagonist is infused into the lateral ventricle of the rats brains, blood pressure does not go up.
Patients received optimal medical treatment with an angiotensin-converting enzyme inhibitor (if not tolerated, an angiotensin receptor blocker was substituted), a beta-blocker, a mineralocorticoid receptor antagonist, and a diuretic.