MMR

(redirected from Mismatch repair)
Also found in: Medical.
AcronymDefinition
MMRMumps, Measles, Rubella (vaccine)
MMRMeasles, Mumps, Rubella
MMRMismatch Repair (DNA)
MMRMassachusetts Military Reservation
MMRMatch Making Rating (gaming)
MMRMajor Molecular Response
MMRMaternal Mortality Rate
MMRMalaysian Medical Resources (est. 1996)
MMRMulti Mode Receiver
MMRMulti Master Replication
MMRMulti Media Router
MMRMulti Media Recording
MMRBurma (ISO Country code, now Myanmar)
MMRModified Modified Read
MMRMulti-Mode Receiver
MMRMass Market Retailers
MMRMiddle Mississippi River
MMRMarc's Modified Ringer's (laboratory solution)
MMRMeet Me Room (point of interconnection in a video/audio conferencing session
MMRMulti Mode Radar
MMRMolzer Mowery Racing (Golden Valley, MN)
MMRMaster of Marketing Research (University of Georgia)
MMRMildly Mentally Retarded (mildly developmentally disabled is preferred)
MMRMaster Model Railroader (NMRA)
MMRMovimiento Manuela Ramos (Spanish; Peruvian women's group)
MMRModerated Multiple Regression
MMRMerchant Marine Reserve
MMRMulti-Mission Radar (Army)
MMRMain Machinery Room
MMRMemory-Mapped Register
MMRMoney Market Rate
MMRMilitary Munitions Rule
MMRMarine Mammal Regulations (Federal Fisheries Act; Canada)
MMRMask-Mounted Regulator (respirator system)
MMRMultimode Radar
MMRManpower Mobilization Request
MMRMaximum Medical Recovery (Workplace Safety and Insurance Act, RSO 1998, Canada)
MMRMedical Magnetic Resonance (imaging)
MMRMe Meo de Risa (Spanish hash tag)
MMRMinimum Maintenance Road (various locations)
MMRMachinist's Mate, Refrigeration (US Navy)
MMRMinimum Marketable Release (market testing)
MMRMetamorphosis Medical Retreats (Vancouver, BC, Canada)
MMRMagnetometric Resistivity
MMRMazda Motor Russia
MMRMass Miniature Radiography
MMRMobile Multi-Hop Relay
MMRMegalocornea-Mental Retardation Syndrome
MMRMulti-Mode Radio
MMRMinimum Military Requirement
MMRMobile Medical Response, Inc. (ambulance service provider)
MMRMaterial Master Records
MMRMonthly Management Review
MMRModular Multiband Radiometer
MMRMobile Meter Reading (of electricity meters)
MMRMixed Media Router
MMRMaster-Master Replication (databases)
MMRModular Mini Refinery (various locations)
MMRMinimum Marginal Return
MMRMobilization Material Requirement
MMRMinoan-Mycenaean Religion (Bronze Age, Greece)
MMRMan Made Rock (construction)
MMRMultiband Multimode Radio
MMRMission Requirements Review
MMRMarble Mountain Ranch (Somes Bar, CA)
MMRMultimode Radiometer
MMRManagement Milestone Record
MMRMultimission Receiver
MMRMaintenance Management Review
MMRMobile Mission Recognition
MMRMediabase Music Research
References in periodicals archive ?
11) These microsatellite-unstable tumours showed distinct clinical and pathological features including proximal location, high-grade and/or mucinous histology, the presence of tumour-infiltrating lymphocytes and mismatch repair gene deficiency, most frequently in the hMLH1 and hMS[H.
Lynch syndrome derives from germline mutations in DNA mismatch repair genes, most often MLH1, MSH2, and MSH6.
Exton, PA) announced the issuance of United States Patent 6,921,666 covering the regulation of mismatch repair, a powerful process for generating functional diversity in yeast, to yield sibling cells exhibiting desirable phenotypes for target discovery, drug screening and/or product development.
She and colleagues recently uncovered deficiencies in mismatch repair genes in some men with testicular failure, predominantly those with Sertoli-cell-only syndrome (Moi.
The new colon panel will assist in the quantitation of immunohistochemistry stains for four mismatch repair biomarkers.
The tests detect certain proteins associated with a DNA repair mechanism called mismatch repair (MMR), and aid in differentiating between sporadic colorectal cancer and probable Lynch syndrome, a hereditary form of colorectal cancer.
Food and Drug Administration (FDA) has approved Opdivo (nivolumab) injection for intravenous use for the treatment of adult and pediatric (12 years and older) patients with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (mCRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan.
Under the partnership, Bristol-Myers Squibb will investigate the safety, tolerability and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumours where the tumours are proficient in mismatch repair (MSS mCRC pMMR).
20) In addition there is utility in identification of ovarian cancer related to Lynch syndrome, which has potential implications with regard to immune modulator therapies currently being investigated in tumors with mismatch repair deficiencies.
The most commonly inherited CRCs are familial adenomatous polyposis (FAP) and hereditary non-polyposis colon cancer (HNPCC) or Lynch syndrome (LS, as it is referred to when a disease-causing mutation is identified in the DNA mismatch repair genes).
Microsatellite instability (MSI) [3] is a form of genomic instability that occurs because of failure of the mismatch repair (MMR) system to correct either insertion or deletion of repeating units during DNA replication.