The product of this reaction is known as Ruhemann's purple (Rp) [3-4].The literature review shows that study of reactions of ninhydrin is a subject of more interest and some of the useful reactions such as amidoalkylation, Knoevenagel condensation , oxidation [7,8], reduction [9,10], reaction with enols and aromatic compounds , synthesis of heterocyclic compounds , Friedel-Crafts type reaction [13-16], Kolbe-Schmitt , Passerini , Wittig  and Morita-Baylis-Hillman  have been investigated in this area.
Kim, A Practical Synthesis of Morita-Baylis-Hillman Adducts of Aryl Vinyl Ketones Catalyzed by a Proton Donor, Bull.
Bharadwaj, "Intramolecular Morita-Baylis-Hillman and Rauhut-Currier reactions.
Shi, "The Morita-Baylis-Hillman (MBH) and Hetero-MBH Reactions," Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications, vol.
Takizawa, 6.9 C-C Bond Formation: (aza) Morita-Baylis-Hillman Reaction Comprehensive Chirality, vol.
de Oliveira et al., "Synthesis and activity of novel homodimers of Morita-Baylis-Hillman adducts against Leishmania donovani: A twin drug approach," Bioorganic & Medicinal Chemistry Letters, vol.
Batra, "Applications of morita-baylis-hillman reaction to the synthesis of natural products and drug molecules," Current Organic Chemistry, vol.
Vasconcellos, "Morita-Baylis-Hillman adducts: Biological activities and potentialities to the discovery of new cheaper drugs," Bioorganic & Medicinal Chemistry, vol.
Another paper showed the Morita-Baylis-Hillman
adducts (MBHA) are a novel group of synthetic molecules that act as anti-inflammatory by modulating inflammatory mediator expression in RAW264.7 macrophages and adenocarcinoma colorectal human HT-29 cells.
The Morita-Baylis-Hillman adducts (MBHA) have been described as anticancer compounds [20-22].
Marques-Santos, "Antimitotic activity on sea urchin embryonic cells of seven antiparasitic Morita-Baylis-Hillman adducts: a potential new class of anticancer drugs," Medicinal Chemistry, vol.
Bomfim et al., "Synthesis, cytotoxic activity on leukemia cell lines and quantitative structure-activity relationships (QSAR) studies of Morita-Baylis-Hillman adducts," Medicinal Chemistry, vol.