Institute of Medicine criteria for diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome Patient has each of the following three symptoms at least half of the time, to at least a moderately severe degree: * A substantial reduction or impairment in the ability to engage in preillness levels of occupational, educational, social, or personal activities that persists for >6 months and is accompanied by fatigue, which is often profound, is of new or definite onset (not lifelong), is not the result of ongoing excessive exertion, and is not substantially alleviated by rest.
National Institutes of Health Pathways to Prevention Workshop: advancing the research on myalgic encephalomyelitis/chronic fatigue syndrome. Ann Intern Med 2015;162:860-5.
17 patients (12 female and 5 male) who each met the Fukuda criteria for myalgic encephalomyelitis/chronic fatigue syndrome
were studied before and after 4 sauna treatments, given at 2-day intervals, with fasting, venous blood samples, and urine samples taken before the first and immediately after the last sauna treatment.
Myalgic encephalomyelitis/chronic fatigue syndrome: Clinical working case defintion, diagnostic and treatment protocols.
Contrasting case definitions for chronic fatigue syndrome, Myalgic encephalomyelitis/chronic fatigue syndrome, and Myalgic encephalomyelitis.
Pain inhibition and postexertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome
: an experimental study.
The Nathan/Van Konynenburg study showed a number of biochemical changes in myalgic encephalomyelitis/chronic fatigue syndrome
(ME/CFS) and fibromyalgia patients, changes that improved, apparently along with symptoms in response to their therapeutic regimen.