MRTF

(redirected from Myocardin-Related Transcription Factor)
AcronymDefinition
MRTFMyocardin-Related Transcription Factor (leukemia)
MRTFMulti-Role Task Force (gaming)
MRTFModulation Rate Transfer Function (physiology)
MRTFMission Readiness Task Force
MRTFMissouri Retired Teachers Foundation (Jefferson City, MO)
MRTFMaximum Remaining Time First
MRTFMultidrug-Resistant Typhoid Fever (infectious diseases)
References in periodicals archive ?
Cultured tubular epithelial cells in diabetic conditions and kidneys of diabetic mice revealed an increased expression of myocardin-related transcription factor A (MRTF-A), which led to the recruitment of p300 and WDR5 to collagen promoters, resulting in transcriptional activation [71].
Abbreviations [alpha]-SMA: [alpha]-Smooth muscle actin BMP-7: Bone morphogenic protein 7 CTGF: Connective tissue growth factor DKD: Diabetic kidney disease ECM: Excess extracellular matrix EMT: Epithelial-to-mesenchymal transition FN-1: Fibronectin-1 HAT: Histone acetyltransferase HDAC: Histone deacetylase HMT: Histone methyltransferase MRTF-A: Myocardin-related transcription factor A PAI-1: Plasminogen activator inhibitor 1 Smad: Mothers against decapentaplegic homologue STZ: Streptozotocin TGF-[beta]1: Transforming growth factor [beta]1 TSA: Trichostatin A.
This effect depends on the nuclear translocation of the myocardin-related transcription factor A (MRTF-A), also a G-actin binding protein [23].