MyoD, myoblast determination protein; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PAX7, paired box 7; Myf5, myogenic factor
5; MyoG, myogenin; FHL1, four and a half LIM domains 1; NFATcl, nuclear factor of activated T cells 1; D.W, distilled water.
As is shown, the expression of FGF21 and its coreceptor [beta]-Klotho as well as myogenic factors
MyoD, MyoG, and Myf5 was increased at the transcriptional level in response to early myogenic differentiation (Figure 1(a)).
Dandelion extract promoted the release of myogenic factors
Although MyoD converts undifferentiated myoblasts into myotubes, muscle development is not dramatically altered in MyoD mutant mice, suggesting that functional redundancy of other myogenic factors
such as Myf5 and Mrf4 may compensate for dysfunctional activity of MyoD [19,20].
Three polymorphisms in the porcine myogenic factor
5 (MYF5) gene detected by PCR-RFLP.
Its cause has not been clarified clearly, and it is assumed to be associated to bladder mucosa, myogenic factors
or neurogenic factors.
As such, it is worth trying to optimize the rASCs' culture environment to enhance the secretion of myogenic factors
Casas et al., "Mitochondrial activity is involved in the regulation of myoblast differentiation through myogenin expression and activity of myogenic factors
," Journal of Biological Chemistry, vol.
that regultate expression of muscle-specific microRNAs.
Response of growth and myogenic factors
in human skeletal muscle to strength training.
Interestingly, the nervous system-based ideas seem more feasible due to (Figure 2) the following: (1) the trophic state of the muscle is determined by the net protein balance and some myogenic factors
However, it should be stressed that myostatin plays an important and positive role during myoblast growth and differentiation by down-regulation of myogenic factors
such as myogenin and Myf5 and contributes to the regulation of fiber-type composition (41-43).