NDMA

(redirected from N-Nitrosodimethylamine)
Also found in: Dictionary, Medical, Wikipedia.
Related to N-Nitrosodimethylamine: NDMA
AcronymDefinition
NDMANetview Distribution Manager Agent
NDMAN-nitrosodimethylamine
NDMANational Disaster Management Agency (various countries)
NDMANonprescription Drug Manufacturers Association (now Consumer Healthcare Products Association)
NDMANorth Dakota Medical Association (Bismarck, North Dakota)
NDMANational Digital Mammography Archive
NDMANational Dimension Manufacturers Association (est. 1985)
NDMANetwork Diversity Multiple Access
NDMANATO Data Management Authority
References in periodicals archive ?
An official from the Directorate General of Pharmaceutical Affairs and Drug Control in Ministry of Health stated that as per information received from the international regulatory organisations and authorities, the contents of N-Nitrosodimethylamine (NDMA) is suspected to cause cancer.
Le ministere de la Sante signale l'apparition d'une impurete, probablement cancerigene, qui a ete detectee dans certains medicaments contenant du valsartan fabrique par la societe Zhejing Huahai Pharmaceutical Co-Chine, souligne la meme source, ajoutant que cette alerte concerne plusieurs pays au niveau mondial suite a la detection de la N-nitrosodimethylamine (NDMA) dans la substance active [beaucoup moins que]Valsartan[beaucoup plus grand que] fabriquee par Zhejing Huahai Pharmaceutical Co.
Second hand smoke has higher amounts of several toxic chemicals like benzene, 4-aminobiphenyl and as much N-nitrosodimethylamine as one who has smoked 75 cigarettes
Recently, N-nitrosodimethylamine (NDMA) has been identified as a possible water disinfection by-product and has been detected in water treatment plants in the US and Canada that use chloramines as a disinfectant.
Unlike other water purification providers, Trojan's design is closed vessel and pressurized and does not use microfiltration and reverse osmosis treatments--processes that often allow small molecular contaminants, such as N-nitrosodimethylamine (NDMA) to pass through.
Effect of ascorbic acid and green tea on endogenous formation of N-nitrosodimethylamine and N-nitrosopiperidine in humans.
Table 1 presents data on the toxicity and carcinogenicity of five volatile NA (NDMA = N-nitrosodimethylamine, NDEA = N-nitrosodiethylamine, NPYR = N-nitrosopyrrolidine, NPIP = N-nitrosopiperidine, NDBA = N-nitrosodibuthylamine) from the literature [2, 3].
We have found that 40% of the N-nitrosodimethylamine is lost during the solvent evaporation step, this loss is appropriately accounted for in the calculations of the concentrations.
The investigation into possible contamination of sartan medicines began in 2018, after the nitrosamine N-nitrosodimethylamine (NDMA), was identified in valsartan manufactured at a facility based in China.
The administration found 43 contained animal carcinogens of the type N-Nitrosodimethylamine or N-Nitrosodiethylamine, although not all the drugs that were recalled have been tested yet, NOWnews reports.
The FDA first recalled valsartan medicines back in July, after the Chinese company that makes the drugs, Zhejiang Huahai Pharmaceuticals, found a contaminant called N-nitrosodimethylamine (NDMA) in several batches of its active ingredient, valsartan API.
The discovery means that some of the 10 billion pills containing valsartan sold worldwide last year to prevent heart attacks and strokes had traces of N-nitrosodimethylamine (NDMA), classified as a probable human carcinogen.