(10) In their multicenter trial, the authors sought to determine if there was a survival benefit with HIPEC in patients with stage III ovarian, fallopian tube, or peritoneal cancer treated with NACT
. Eligible participants initially were treated with
During 1994-2008 only 6% and 22% of patients in Ontario received NACT
or ACT respectively.
Cui et al., "Efficacy of HIPEC as NACT
and postoperative chemotherapy in the treatment of advanced-stage epithelial ovarian cancer," ClinicalTrials.gov Identifier: NCT03180177.
A total of 84 patients who received NACT
prior to surgical resection without achieving complete pathological response had tissue from their surgical resections available for analysis.
 A few patients were treated with primary radiotherapy (n=7) or NACT
(n=15), with varying responses.
The aim of the current study was to evaluate the possible association between major redox-regulating proteins and chemoresistance in a cohort of patients with primarily inoperable breast cancers treated with NACT
. The prognostic value of the studied proteins was also assessed, both in pre-NACT and postoperative samples.
In contrast, for patients with stage IV disease, our results confirm that NACT
is noninferior to PCS for survival, with fewer ICU admissions and rehospitalizations, which suggests that NACT
may be preferable for patients with stage IV ovarian cancer," they wrote in the Journal of Clinical Oncology (2016.
[sup] Currently, neoadjuvant chemotherapy (NACT
) for advanced cervical cancer is widely utilized in countries such as Japan, Korea, and Italy.
The second option is to give neo-adjuvant chemotherapy (NACT
), followed by surgery.
This gene participates in the N-terminal caspase recruitment (NACT
) protein domain family, being involved in the response of Toll-like receptors transduced inflammatory stimuli .
Induction or neoadjuvant chemotherapy (NACT
) prior to definitive local treatment has been used in carcinoma of maxillary sinus and response rates in the region of 60-70% have been reported.