NALP3


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AcronymDefinition
NALP3Nacht Domain-, Leucine-Rich Repeat-, and PYD-Containing Protein 3
References in periodicals archive ?
Tschopp, "Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration," Cell Death & Differentiation, vol.
MKD is apparently caused by interference with the geranylation of the small GTPases Rac and Rho, resulting in activation of the NALP3 inflammasome, and release of interleukin 1[beta] [9, 10].
Tschopp, "Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica," Science, vol.
NLRP[3.sup.-/-] or Caspase-[1.sup.-/-] mice showed reduced brain Caspase-1 and IL-1[beta] activation, protected spatial memory, and enhanced A[beta] clearance [31], indicating that the activation of the NALP3 inflammasome by A[beta] may be a critical component of the inflammatory response in AD.
Previous study has found that high extracellular potassium concentration (130 mM) can block the activation of NALP3 inflammasome and inhibit the activation ofcaspase-1.
Expression and regulation of the NALP3 inflammasome complex in periodontal diseases.
El inflamasoma NLRP3 esta constituido por la proteina receptora NLRP3 (tambien conocida como NALP3 y criopirina), la ASC y la caspasa-1.
Sarndahl, "Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation relation to common inflammatory diseases?" Arthritis and Rheumatism, vol.