Abbreviations AUC: Area under the curve CRF: Corticotrophin-releasing factor CSS: Constipation Scoring System CTT: Colonic transit time GI: Gstrointestinal GSRS: Gstrointestinal Symptom Scoring Rate HC: Halthy controls IBS: Irritable bowel syndrome MMC: Migrating motor complex NANC
: Nonadrenergic noncholinergic NTC: Normal transit constipation NTR1: Neurotensin Receptor 1 NTS: Proneurotensin gene STC: Slow transit constipation QoL: Quality of life UTR: Untranslated region.
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such as impaired vasodilatory signaling, nonadrenergic-noncholinergic (NANC
) dysfunction, endothelial dysfunction, oxidative stress, proinflam-matory changes, cavernosal hypercontractility, venoocclusive dysfunction, and hypogonadism.
Data used in this study came from eight commercial pig farms (DYZC, DZZC, JYZC, LESH, MYZC, NANC
, NJPF, and SCBF, which are members of united breeding program of Sichuan province).
Os virus respiratorios tem a capacidade de aumentar consideravelmente a hiper-responsividade bronquica, ao estimularem o processo inflamatorio e aumentarem a disfuncao autonomica local, com aumento significativo da producao de neuropeptideos (substancia P, neurocininas A e B etc.) pelas fibras nervosas nao adrenergicas/ nao colinergicas (NANC
) da submucosa.
As an important signalling molecule in GI tract, nitric oxide (NO) is a non-adrenergic, non-cholinergic (NANC
) inhibitory neurotransmitter modulating the blood flow, gut motility, secretory and immunological function (Cho 2001; Sobko et al.
Non-adrenergic, non-cholinergic (NANC
) neurotransmission also plays a role in bronchodilation.
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The national association that represents this movement today seeks "to promote the cause of biblical counseling and the doctrine of the sufficiency of the Scriptures," with a history of trying "to tear down the slums of psychology and level the ground" (NANC