Among patients who were switched from placebo to Otezla at week 16, NAPSI
clearance at week 32 was achieved by 15.5% (n=37/239) and 26.1% (n=6/23) of patients, respectively.
Their mean baseline NAPSI total score was 28.3, compared with 24.8 for the ustekinumab group.
More than one-quarter of patients in the ixekizumab arm had a baseline NAPSI score greater than 43, whereas the top quartile of nail psoriasis severity in the ustekinumab group began with a NAPSI score above 34.
In this study, we aimed to compare the therapeutic efficacy between TI iontophoresis and topical calcipotriol/betamethasone dipropionate regarding nail bed score, matrix score, and total NAPSI.
NAPSI of both hands' fingers was calculated at baseline andsix monthlyfollow-upsbyawell-traineddermatologist in line with six monthly triamcinolone acetonide iontophoresis sessions and daily application of calcipotriol/betamethasone dipropionate ointment for six months.
Severity Index (NAPSI) score of the hands and feet of [greater than or equal to] 10 and a Psoriasis Scalp Severity Index (PSSI) score of [greater than or equal to] 10 were included in the study.
The improvement of nail psoriasis was measured using the NAPSI and the improvement of scalp psoriasis was measured using the PSSI.
We correlated the PBMC population distributions and PD-1 expression with characteristic of psoriasis, that is, duration and the age of the disease onset and psoriasis severity expressed by PASI, BSA, IGA, NAPSI
, and DLQI (Table 3).
The primary efficacy measures used were single hand Nail Psoriasis Severity Index (shNAPSI) for all of the nails on one hand and modified target NAPSI
(mtNAPSI) for the single most severely affected nail on both hands.
The programme of Intercultural education and other educational programmes for the education of minorities, including the teaching of Greek as a second language (NAPSI
[Hebrew text omitted] lo' yada 'ti napsi
, literally "I did not know myself." A fixed idiom denoting the unexpectedness of the event described in the next clause, approximately meaning: "Before I knew myself [such and such happened]".
Peter van de Kerkhof, chairman of dermatology at Radboud University, said he sees the NAPSI
(Nail Psoriasis Severity Index) being used in lots of clinical trials in psoriasis.