NAT1

AcronymDefinition
NAT1N-Acetyl Transferase 1
References in periodicals archive ?
specimen, NAT1, UGT1A10, and GSTP1 were expressed moderately to highly
Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption.
N-acetyltransferase-1 (NAT1) and N-acetyltransferase-2 (NAT2) are encoded by NAT1 and NAT2 in human chromosome 8 (Blum et al.
2 mM dNTP mix, 20 pmol of each primer (B-MDIEA-NAT1 & VPKHGD-X-NAT1 for NAT1, FP1-NAT2 & RP1-NAT1 for NAT2, Act b1 & Act b2 for beta-actin), cDNA template corresponding to the amount synthesized from 50 ng of total RNA and 2 units of DyNAzyme DNA polymerase.
The coefficient for NAT1, the control variable for Korean subsidiaries of US MNCs, is statistically significant and positive.
2 mM dNTP mix, 20 pmoles of each primer (B-MDIEA-NAT1 & VPKHGD-X-NAT1 for NAT1, FP1-NAT2 & RP1-NAT2 for NAT2, Act b1 & Act b2 for beta-actin), cDNA template corresponding to the amount synt hesized from 50 ng of total RNA and 2 units of DNA polymerase.
We believe that the discrepancies between phenotypes and genotypes suggest possible problems in phenotyping or the presence of another factor that contributes to the variability in NAT2 activity, such as the NAT1 gene.
Amplification was done in two steps, primary and secondary PCBs, to differentiate NAT2 from its family member gene NAT1.
This is exemplified in Figure 3 where the dashed gray line represents the risk profile for the most common genotypes modeled from the 12 asthma susceptibility genes (group 1 variants) and the solid blue line shows the risk profile when the NAT1 variant is added.
1998) provided evidence for a three-way interaction between NAT2, NAT1, and smoking that modifies bladder cancer risk such that individuals who smoke and have NAT2 slow acetylator alleles in combination with the high-activity NVAT1*10 allele (homozygotes or heterozygotes) have heightened bladder cancer risk.